In the past few years, lipid nanoparticles have been in the spotlight for their role in mRNA vaccines, but exosomes are often called ‘nature’s lipid nanoparticles’. As a subset of extracellular vesicles, they could reshape the future fields of drug delivery and diagnostics. Their unique physical properties (innate stability, biocompatibility, and the ability to cross the blood-brain barrier) provide many advantages in the future.

This peer-reviewed publication in ACS Nano uses the CAS Content Collection to examine the multifaceted benefits of exosomes in drug development and diagnostics. This includes an examination of the historical breakthroughs, the potential use as a delivery vehicle, and its emerging role in diagnostics.