CAS Insights^TM

Exosomes – nature's lipid nanoparticle, a rising star in drug delivery and diagnostics

Bioorthogonal chemistry is a set of methods that use the chemistry of non-native functional groups to analyze biology in living organisms.

Ammonium nitrate has the power to feed billions, yet when stored improperly is like a bomb waiting to happen. How can we make this fertilizer safer? Learn about emerging science, safer alternatives, and best practices for safe storage and transport.

Explore lipid nanoparticles: from origins to COVID vaccines and beyond. Discover emerging trends in publications and milestones. Uncover future applications in vaccines, drug delivery, and non-therapeutic fields like agro-chemistry, cosmetics, and food science. Learn how these particles are shaping

Learn more about cytokine storms and their role in both immunity and severe infection with COVID-19 and additional viral infections. This overviews emerging trends and insights on publications, milestones, and future applications to minimize the impact of cytokine adverse effects.

Learn more about the hidden greenhouse gas emissions of plants, a more sustainable approach to fertilizer production, and new approaches to make phosphorus more recyclable.

Deformulation is the process of reverse-engineering the composition of known formulations. This publication shows the value of consistent and highly structured representations in predictive models.

If you are producing fertilizers, phosphates, or any of our critical agricultural products, you know sustainability is a big challenge. Join us for the latest in phosphate recycling, sustainable ammonia production, and alternative fertilizer production.

Research and development teams amass huge quantities of complex data which, if exploited correctly, can be a useful information source to improve decision-making and drive innovation.

Visual infographic of nuclear energy’s key benefits of an efficient fuel source, a low emissions option (compared to coal and natural gas) and new recycling efforts that minimize nuclear waste.

Expert panelists include Dr. Benjamin Ebert, the chair of Medical Oncology at the Dana-Farber Institute, Dr. Phil Chamberlain, the co-founder, President, and CEO of Neomorph, and Janet Sasso, an information scientist specializing in Life Sciences at CAS.

Timeline showing key reactions and applications culminating in 2022 Nobel Prize in Chemistry

Learn about the basics of click chemistry and bioorthogonal chemistry that was recently awarded the 2022 Nobel Prize in Chemistry. Read about emerging trends, insights on publication trends, and future applications of bioorthogonal chemistry.

When mRNA (messenger RNA) vaccines are injected into a patient, tiny lipid vesicles transport mRNA molecules through the body fluids and merge with immune cells, called antigen-presenting cells (APCs).

Drug development is rapidly changing, which requires pharma companies to pivot. This is where AI drug development comes in, applying new technology to tackle an old problem.

Scientists are searching ways to stop the spread of COVID-19, and the ACE2 receptor is one of the most promising targets.

This blog details the recently published CAS indicator of drug innovation based on the structural novelty of new molecular entities (NMEs) which may better assess innovativeness of new drugs.

Find out how companies improve their prediction accuracy, obtain Breakthrough Technology Status and shorten the development and review time of new drugs by leveraging CAS advanced machine learning methods.

One approach that has gained momentum since the 1990s is green chemistry, a scientific field focused on "the invention, design, and application of chemical products and processes to reduce or eliminate the use and generation of hazardous substances.

Scientists at Bayer expand their understanding into new, useful chemistry by improving the predictive power of a synthesis planning model with scientist-curated reactions from CAS.

This whitepaper explores challenges and opportunities for worldwide patent offices as they seek to ensure sustainability and future growth. It focuses on the application of artificial intelligence-enabled workflow solutions to enhance productivity and patent quality.

Bioorthogonal chemistry is a set of methods using the chemistry of non-native functional groups to explore and understand biology in living organisms.

Learn more about the scientific challenges, emerging technologies, and the financial and environmental implications for recycling lithium ion batteries.

With over 90% of the world’s plastics production requiring fossil fuels, bio-based polymers generated from renewable sources have substantial benefits over traditional plastics – from reducing CO2 emissions, increased biodegradability, and less dependence on fossil fuels. Learn more in our landscape

This insight report explores innovative research and technologies that played crucial roles in Covid-19 vaccine development.