Gain clarity with unique identifiers of chemical substances
CAS Registry Services helps you obtain CAS Registry Numbers® (CAS RNs®), CA Index Names, and substance information for reports, proprietary files, online searching, and regulatory applications.
Ask a questionLooking for CAS Registry Numbers or CA Index Names for known substances?
If you’re looking for a unique substance, simply complete and submit a CAS Registry Lookup service order form and receive results within 24 hours (excluding weekends and holidays). The current cost is $70 per substance name or CAS Registry Number searched.
Also available is CAS Common Chemistry, an open community resource with nearly 500,000 chemical substances from CAS REGISTRY®.
Obtain a CAS Registry Number or CA Index Name for your novel chemical substance with the following steps:
- Review the CAS Registration Criteria Overview and Registry Number Info Requirements, as well as the FAQ below.
- Submit a CAS Registry Services consultation request for nomenclature and/or CAS Registry Number assignment and provide the relevant chemical structure diagrams or descriptive information (including a unique substance identifier limited to 20 alphanumeric characters).
Completing a WHO INN or USAN application?
Consult with CAS Registry Services chemists when you need a CAS Registry Number or to find substance information for reports, proprietary files, online searching, confirmation for an International Nonproprietary Name (INN), or United States Adopted Name (USAN) application.
- Review the CAS Registration Criteria Overview and Registry Number Info Requirements, as well as the FAQ below.
- Submit a CAS Registry Services consultation request along with relevant chemical structure diagrams or descriptive information (including a unique substance identifier limited to 20 alphanumeric characters).

Completing an EPA PMN application?
CAS Inventory Expert Services (IES) helps you obtain CA Index Names and CAS Registry Numbers necessary to complete pre-manufacturing notices for EPA TSCA. Your work with CAS IES will remain confidential.
Follow these steps to ensure a smooth process:
- Prepare: Ensure complete chemical identity for Class 1 and Class 2 substances. Review what "What information must be provided for a CAS Inventory Expert Service request?" and other frequently asked questions below.
- Complete forms: Fill out the EPA PMN form and submit it to both the EPA and CAS, or provide the required substance information to CAS.
- Submit request to CAS: Complete the CAS request form, attaching your completed EPA PMN form.

Want to license CAS REGISTRY data?
Improve your digital R&D workflows and ensure compliance when you license CAS REGISTRY data:
- Integrate CAS Registry Numbers (CAS RNs) into your digital R&D processes.
- Ensure your public data meets regulatory standards.
- Tap into a source with over 275 million unique chemicals.
CAS Registry Services FAQ
What is CAS Registry Services?
CAS Registry Services helps you obtain CAS Registry Numbers® (CAS RNs®), CA Index Names, and substance information for reports, proprietary files, online searching, and regulatory applications, including International Nonproprietary Name (INN) or United States Adopted Name (USAN) applications.
A branch of our service called CAS Inventory Expert Service provides substance identification for EPA TSCA PMN applications under the Revisions of Premanufacture Notification Regulations: Final Rule.
What is CAS REGISTRY?
CAS REGISTRY is the most authoritative collection of disclosed chemical substance information. It covers substances identified from the scientific literature from 1957 to the present, with additional substances going back to the early 1900s, and is updated daily with thousands of new substances.
What experience does the CAS Registry team have?
The CAS Registry Services team consists of chemists who are experienced in substance identification and requirements. Our team also compiles, searches, and maintains the TSCA Inventory for the United States Environmental Protection Agency.
By relying on CAS, you will take advantage of the in-depth knowledge CAS staff have acquired concerning TSCA submission policies. For example, should you request a CAS Registry Number for a hydrated substance to be reported to the EPA, CAS will provide you with the CAS Registry Number for the anhydrous substance along with the guidance that hydrates are excluded from TSCA reporting.
Will my requests be confidential?
Yes. Processing is strictly confidential. CAS maintains extensive security policies and procedures relating to both physical security and the handling of customer-supplied information. These procedures include detailed measures outlining the labeling, handling, tracking, storage of documents, computer access, and verbal communication regarding a given request. Without written permission, CAS will only discuss the details of a request with the individual(s) who submitted it. Our order forms allow you to provide an alternative contact should you wish to grant permission for CAS to discuss the order with an individual(s) other than the submitter(s).
Please note that assigning a new CAS Registry Number to your novel substance makes the substance publicly available in CAS REGISTRY®. If you wish to maintain confidentiality for your substance’s identity, you should request a CA Index Name only. If the assignment of a new CAS Registry Number is requested, your company’s name will not be attributed to the registration.
What does CAS Inventory Expert Services cost?
The below prices cover the chemist’s initial review, standard consultation, and the issuance of CA Index Names, along with CAS Registry Numbers®, at the time of order submission. Additional consultation fees will continue to apply if necessary; each subsequent consultation fee will be $310.
See below to learn what is required for the complete chemical identity of Class 1 and Class 2 substances.
What do other CAS Registry Services cost?
A simple lookup request for an existing CA Index Name or CAS Registry Number costs $70 USD per substance.
When it comes to substance information requests and CAS RN assignment, we work on a time and materials basis. Consultation rates are $335 USD for the first 30 minutes and $195 USD for subsequent 30-minute increments. Processing times may vary based on the complexity and number of substances within a submission. The typical single-substance order will take between 30 and 120 minutes of chemist processing time.
Please note that if, during our chemists' review, we discover errors, inconsistencies, or missing data that require additional consultation beyond the standard consultation, a fee will be applied.
What information must be provided for a CAS Registry Services consultation request?
Consult CAS Registration Criteria Overview and Registry Number Info Requirements to determine complete chemical identity requirements.
What information must be provided for a CAS Inventory Expert Service request?
Include the following for a Class 1 substance, defined as chemical substances that are single compounds composed of molecules with atoms arranged in a definite, known structure. See PMN page 4.
- Molecular formula
- Descriptive chemical name (if possible)
- Structure
For a Class 2 nonpolymeric substance, include the following. See PMN page 4.
- CAS RNs for starting materials
- Process information
- Composition
- Representative structure of final product
For a Class 2 polymeric substance, include the following. See PMN page 5.
- Descriptive chemical name, CAS RN, and percentage of each starting monomer
- Representative structure with monomers linked together
- Free Radical Initiator, CAS RN, and percentage (if needed)
- All monomers and initiators indicated applying the 2% rule
Class 2 substances are chemical substances with a variable composition or a complex combination of different molecules. They can be further subdivided into three subgroups.
- The first subgroup includes substances that can be represented by definite Hill-ordered molecular formulae but have variable structural diagrams.
- The second subgroup includes substances that can be represented by definite molecular formulae but have unknown structural diagrams.
- The third subgroup includes representations of substances that have no definite molecular formula representation and either partial structure diagrams or no structural diagrams - often referred to as UVCBs (Unknown or Variable Composition, Complex Reaction Products, and Biological Materials).
What is the turnaround time for a CAS Registry Services request?
Orders for substance information and CAS RN assignments are processed within 10 working days, starting when all the required information is received. If the chemist processing the order requires more information, you will be contacted, and processing time will restart once the information is received.
A simple lookup request for an existing CA Index Name or CAS Registry Number requires a 24-hour turnaround.
Can I get my results sooner?
Inventory Expert Services can accommodate expedited requests for a three-working-day turnaround for $310 USD per substance. Timing is still dependent on our office having all the necessary information from the customer.
We are not able to offer expedited service for other nomenclature and/or CAS Registry Services assignments at this time.
How are results delivered?
Results are delivered via email.
What if I have questions about my results?
We are available to help you understand the results for your order. If you have questions about the results for your order, please contact us via email or phone. Please note that if significant additional consultation by a CAS chemist is necessary, additional consultation fees may apply. You will be informed in advance if any additional fees will be incurred in the consultation about your results.
Phone: 800-631-1884 (N. America)
614-447-3870 (worldwide)
E-mail: answers@cas.org