Comprehensive insights on lipid-based drug delivery systems
Report summary
Lipid-Based Drug Delivery Systems: Unlock the Future of Drug Delivery examines historic advancements, the current landscape, and the future of lipid-based drug delivery. Leveraging over 200,000 indexed scientific documents from the CAS Content Collection™, our scientists provide actionable insights to help guide the future development of these systems, ensuring your next project has a solid foundation.
Pharmaceutical decision-makers, investors, R&D leaders, and strategists seeking data-driven insights into lipid-based drug delivery innovations will benefit from the insights in this comprehensive report. This data-driven intelligence will help you maintain an edge in the rapidly evolving field of drug delivery.

What is the function of lipids?
Lipids, essential components of biological membranes, possess numerous unique functions that make them viable candidates in many scientific and pharmacological fields. Lipid-based drug delivery is revolutionizing the pharmaceutical industry, with ongoing discoveries about their unique properties driving drug discovery innovations.
The high biocompatibility and versatility of lipids can help overcome common challenges in pharmacological delivery methods, such as poor solubility, low availability, rapid degradation, and off-target effects. Additionally, they encapsulate many compounds, including small-molecule drugs, nucleic acids, and peptides, thereby expanding their therapeutic range.
Lipid nanoparticles and other lipid-based drug delivery systems
From early platforms like simple liposomes to advanced systems such as solid lipid nanoparticles and stimuli-responsive smart lipid systems, the field has experienced remarkable innovation and growth. Engineered lipids—including ionizable, PEGylated, branched-chain, polymerizable, and bioresponsive variants—enable precise and efficient delivery of small molecules, genetic material, and biologics. These advancements reshape treatment paradigms in oncology, infectious diseases, gene therapy, and other diseases, solidifying lipids as a cornerstone of cutting-edge therapeutics.

In Lipid-Based Drug Delivery Systems, we examine a wide range of lipid-based delivery systems. By combining the latest advancements in lipid nanotechnology with insights from preclinical and clinical studies, this report provides a roadmap for the rational design and optimization of lipid nanoparticles and other lipid-based carriers for diverse therapeutic interventions.
The future these delivery systems is promising, driven by advancements in nanotechnology and personalized medicine. These innovations will continue improving the effectiveness, safety, and patient acceptability of therapies while addressing global health challenges and environmental sustainability.
What you will learn about the future of drug delivery
- The unique roles and mechanisms of different lipids used in drug delivery
- The latest data trends and innovation pipelines in lipidic drug carriers
- How lipids are driving advancements in delivery applications
- Leading organizations actively researching lipid-based drug delivery
- Novel approaches to customizing lipids for therapeutic innovations
- Challenges and opportunities lipids pose for the future of drug delivery
Whether you are in R&D, strategy, or investment, Lipid-Based Drug Delivery Systems equips you with the knowledge to innovate and excel in this dynamic field.
Table of contents
The Global R&D Landscape for Lipid-Based Drug Delivery Technologies – CAS TrendScape™ Map
Cutting-Edge Research and Publication Trends
Leading Innovators: Top Academic Organizations and Commercial Companies
Recent Breakthroughs Influencing Future Directions
Current Trends in Major Lipid Classes
Lipid Innovations Shaping the Future of Drug Delivery
- Cationic Lipids – The Silver Bullet in Nonviral Gene Delivery
- Ionizable Cationic Lipids – The Rising Star in Drug Delivery
- PEGylated Lipids – Making Drug Delivery Systems Invisible
- Targeting Ligands for Precision Medicine
- Stimuli-Responsive Lipids – Smart Delivery Systems
- Cross-linkable/Polymerizable Lipids – Enhanced Stability
- Lipids as Imaging Agents for Real-Time Monitoring
- Theranostic Lipids – Combined Diagnostics and Therapy
- Lipid-Drug Conjugates (Lipidic Prodrugs): Better Pharmacokinetics, Lower Toxicity
Polar Lipids – Back to Basics
Neutral Lipids
Lipid Stereochemistry
Natural Lipid Extracts
Synthetic Biology: Lipid Synthesis Revolution
Chemical Synthesis Pathways
- Ionizable Lipids
- Cationic Lipids
- PEG Lipids
Leading Companies in Lipid Synthesis and Methodologies
Lipid Molecular Shape
Lipid Phase Transition Temperatures
Lipid Polymorphism and Mesomorphism in Drug Delivery Systems
Impact of Lipid Phase Transitions in Drug Delivery
- Solid – Liquid Crystalline (Melting) Transition
- Lamellar – Nonlamellar Transition
Liposomes – The Pioneers of Lipid DDS
Lipid Nanoparticles (LNPs) – Breaking Boundaries
- Solid Lipid Nanoparticles and Nanostructured Lipid Carriers – Aiming for Perfection
- Cationic/Ionizable Lipid Nanoparticles and Lipoplexes: The Nucleic Acid Vectors
Micelles: Small Size and Enhanced Permeability
Advanced Emulsion Systems: Microemulsions and Nanoemulsions
Ethosomes: Efficient Skin Penetration
Exosomes: Nature-Inspired Drug Carrier
Virus-Like Particles (Enveloped)
Hybrid Lipid Nanoparticles: Combining Strengths
Others
Key Trends of Lipid-Based Drug Delivery Systems
Formulation Techniques
Characterization Techniques
Conventional Routes of Administration for Lipid DDS
Innovative Delivery Routes for Lipid DDS
Cancer
Infectious Diseases
Nervous System Disorders
Metabolic Disorders
Cardiovascular diseases
Clinical Trials
Regulatory Approved Drugs Utilizing Lipid-Based DDS
Advantages of Lipid-Based Drug Delivery Systems
Overcoming Challenges in Lipid-Based Drug Delivery
Future Directions
Methodology
The CAS Content Collection, the world’s largest human-curated scientific database, forms the data foundation of Lipid-Based Drug Delivery Systems: Unlock the Future of Drug Delivery, ensuring unparalleled accuracy, depth, and reliability. Our leading lipid chemistry and drug delivery experts have collaborated with data scientists and business leaders to generate insights that surpass conventional literature reviews using advanced analytical capabilities and state-of-the-art data tools.
Drawing from 200,000 carefully curated journal articles and patents from 2003 to 2024, this report delivers a unique competitive edge by quantifying critical elements of lipid-based drug delivery. We transform complex data into actionable intelligence by classifying key scientific terms, counting patents by patent families, tracking chemical substances, and mapping synthesis reactions.
Search strategy
CAS subject-matter experts meticulously crafted and iteratively refined our search query to minimize irrelevant data while ensuring a holistic capture of all significant developments.
Why CAS?
CAS, a division of the American Chemical Society, is a world-leading scientific information solutions organization focused on transforming lives through the power of science. We curate, collect, and analyze published scientific literature to create solutions, including CAS SciFinder®.
By staying up to dates with published literature, scientific advancements, and the happenings of each related industry, we bring together unique expert insights unavailable anywhere else.
Contact us
For questions related to Lipid-Based Drug Delivery Systems: Unlock the Future of Drug Delivery, please reach out to the CAS Customer Center.
- Instant access via PDF
- More than 100 custom-designed figures, tables, and synthetic schemes
- Over 1,200 published references and hundreds of unique substances with CAS Registry Numbers®
- Analysis of active commercial and academic research trends