Plan confidently with retrosynthesis software built on CAS data
Work smarter and faster to stay ahead of the competition with retrosynthetic analysis software powered by best-in-class data, curated and indexed by CAS experts.
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Integrated knowledge and insights
Access the information you need to advance your research in one place with CAS SciFinder®. Move seamlessly from your plan to reactions, commercial sources, and more.
Unbeatable information coverage
Plan with the most relevant information from our exhaustive reactions database, updated daily to include the latest research.
Expert verification and curation
Rely on the power of human curation to ensure your retrosynthesis is based on chemically sound reaction data.
Begin from any starting point
Access retrosynthesis software from a substance at any point in CAS SciFinder with the Start Retrosynthetic Analysis button. Search your compound's name, CAS Registry Number®, or drawn structure, or select substances from reference and reaction results.
Customize your retrosynthesis model
Create a retrosynthesis plan for your unique needs with advanced options. Direct your search toward specific parts of the molecule, set cost limits for starting materials, and adjust the degree of evidence supporting predicted reactions, fine-tuning your analysis.
Explore your retrosynthesis plan
Find all the important details of your retrosynthesis plan in one place, including yield, cost, and stereochemistry. Quickly identify predicted steps and modify the plan to include or exclude them using the toggle switch.
Access reaction details and evidence
Delve into expert-curated insights for your entire retrosynthesis plan in the Evidence Drawer. View details including reagents, catalysts, solvents, and links to evidence and alternative steps for each reaction in your plan, enabling you to make better decisions faster.
Discover alternative reaction steps
Explore alternative steps for the reactions in your retrosynthesis plan. Choose from alternative reactions, ranked by relevance to the starting molecule, and filter by Alternative Step Type and Stereochemistry to return options tailored to your needs.
Exclude unwanted routes
Streamline your retrosynthesis plan by excluding entire steps or individual reactants. Once excluded, the retrosynthetic analysis software will automatically update based on available alternative steps. You can reintroduce excluded steps or reactants at any time.
Choose CAS SciFinder for retrosynthesis software you can trust
Rely on CAS data and expert human curation to power your retrosynthetic analysis.
