CAS BioFinder Discovery Platform™

Move your drug discovery program to the next stage with comprehensive pharmaceutical data embedded into AI-enhanced predictive technology and knowledge graphs, searchable by ligand, target, and disease.

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Confidently advance drug discovery

Working through the literature to find disease targets, plan structure-activity relationship studies, and assess the potential for off-target interactions takes time and risks missing key information. The CAS BioFinder Discovery Platform brings together the data and solutions needed across drug discovery workflows, including discovery biology and medicinal chemistry.

CAS BioFinder™

With CAS BioFinder, you can explore connections between ligands, targets, and diseases and run AI-enhanced predictive bioactivity models with data derived from existing literature.
This ensures you always have the most relevant results.

In addition to existing and predicted bioactivity, ligand, sequence, disease, and biomarker data, CAS BioFinder also integrates 3D protein models and details to save time and advance your drug discovery program.

Life sciences capabilities in CAS SciFinder®

Expand the capabilities of CAS SciFinder with detailed bioactivity data tables, biological sequence searches, and seamless integration with searches in CAS BioFinder.

"CAS BioFinder provides a centralized database for drug discovery. It tells you everything that’s been published in patents and literature and has associated pharmacology pathways, metabolism, and nearby chemical neighbors. A lot of people in drug discovery are going to different databases for each line function, but CAS BioFinder is a nice way of centralizing that."

Structural biologist, CAS BioFinder development partner

Enhanced biological data for your drug development success

Designed to support the needs of biology-based inquiry and sequence searches, the CAS BioFinder Discovery Platform pulls from new data types, authorities, and connections in the CAS Content Collection™.

With enhanced bioactivity data on ligands, their interactions with proteins and diseases, related biomarkers, and pathways, you have better access than ever to the full range of data needed for drug development.

Explore CAS life sciences data

What scaffolds and molecules are associated with your disease of interest?

Investigate associations between diseases, targets, pathways, and ligands, with references and experimental conditions to support the evidence.

What molecules are known or likely to be active against your target of interest?

Find normalized bioactivity data and similar scaffolds to investigate and use AI-enhanced tools to predict the bioactivity of ligands against a specific target.

How will your molecules interact with proteins and impact biological processes?

Predict targets and bioactivity values for known and novel molecules and explore pathways and cellular processes affected by the molecule-protein interaction.

Which molecules will make the best leads?

Focus on molecules with specific drug-like properties or that have already been approved as drugs, screen for potential safety issues, and identify known and potential metabolites.

What biomarkers are relevant to your disease of interest?

Discover evidence-based connections between biomarkers and diseases and research their involvement in biological pathways.

Bring therapies to life faster with reliable and actionable drug discovery data insights through the CAS BioFinder Discovery Platform. 

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