CAS InsightsTM
Accelerating your scientific progress by revealing unique connections and perspective at the intersection of science, technology, and innovation.
![Inflamed knee healing, illustration](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/66bfc7b8eb97a3bdcd3845cc_GettyImages-1607119465_CAS-Insights-Hero-Image.jpeg)
![Inflamed knee healing, illustration](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65664db43ac339e9410b9589_Janet-Sasso_0.webp)
Biomaterials are making an impact on health and medicine. Experts from CAS, Ortholevo, and Westlake University discuss the full landscape.
![Two Radiologists Looking At MRI Scan On Computer](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/668ed10827199a8526c23c23_GettyImages-1312649676_CAS-Insights-Hero-Image.jpg)
![Two Radiologists Looking At MRI Scan On Computer](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65664c5adf81e2c0183b3914_Rumiana-Tenchov2.webp)
Uncover the latest advancements in understanding and treating neurodegenerative diseases like Alzheimer’s, Parkinson’s, and Huntington’s.
![Multi-walled Carbon Nanotube](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/667453f114451ce2a6ea2d3f_GettyImages-181900530_CAS-Insights-Hero-Image.jpg)
Biomedicine, batteries, and more could be revolutionized by carbon nanotubes. See the full range of their applications.
![middle aged woman with mobility issues](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6655f4d45b39fb2df7add062_GettyImages-1172515013_CAS-Insights-Hero-Image.jpg)
![middle aged woman with mobility issues](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65664c5adf81e2c0183b3914_Rumiana-Tenchov2.webp)
Sharing new research on inverse vaccines, potential new breakthroughs in treating autoimmune diseases like multiple sclerosis, type 1 diabetes and celiac disease
![Male Doctor and Patient Examining brain MRI](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6655f72f393c15ac97050e32_GettyImages-1412852343_CAS-Insights-Hero-Image.webp)
![Male Doctor and Patient Examining brain MRI](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65664c5adf81e2c0183b3914_Rumiana-Tenchov2.webp)
Biomarkers, personalized medicine and gene therapies are fueling research breakthroughs. Discover new treatments targeting genetics and protein buildup to manage this devastating disease.
![Organic, bio cosmetics healthy concept with Petri Dishes](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6650c9a5a28beeec4baafb63_GettyImages-1357162123_CAS-Insights-Hero-Image.jpg)
Learn about the shift towards sustainable and natural ingredients in cosmetics, supported by data from the CAS Content Collection™.
![Human brain](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65738d1500058c938ae33bcb_GettyImages-1410795090_CAS-Insights-Hero-Image.webp)
Bioelectronics: Merging man and machine. Explore the latest advancements in brain-computer interfaces, materials, and their potential to revolutionize medicine.
![baby feet](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6650cdfaa290bc2f4cefcae0_GettyImages-1530326519_CAS-Insights-Hero-Image.webp)
![baby feet](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6650cee28206339303109d50_jean-marc-150x150-headshots%20(1).webp)
Nanoscale materials are bridging the gap between nanotechnology and bioelectronics, paving the way for highly sensitive biosensors.
![Molecular model of messenger ribonucleic acid mRNA](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/66421322277b4accaff6f2ee_GettyImages-1450368712_CAS-Insights-Hero-Image.webp)
Different types of antisense oligonucleotide therapies, such as exosomes and nanoparticles, offering new hope in genetic medicine.
![Human cell and virus cells](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6642166d4ee026b29025ce35_GettyImages-182506763_CAS-Insights-Hero-Image.jpg)
![Human cell and virus cells](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65552931e98e0f62c065620b_CASGENENGIMG100984221209-Jen-Sexton-headshot.webp)
Learn how emerging trends in AI are impacting CBRNE threat detection and mitigation.
![A digital art image depicting a dark, circular center surrounded by a radiant halo of glowing blue and green light strands, resembling an eye or an abstract explosion. The background is a deep blue, enhancing the vibrancy of the colors.](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6642179c8cd214f452d9591f_GettyImages-1495604593_CAS-Insights-Hero-Image.jpg)
Unlock the potential of nanotechnology. Explore breakthroughs and challenges in energy, biomedicine, and more in our executive summary.
![Abstract digital artwork featuring vibrant, multicolored peaks and valleys. The image showcases a dynamic blend of pink, purple, blue, and black hues, creating a visually striking and futuristic landscape with a sense of depth and movement.](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/662a57de9be24d9652ba4b3b_GettyImages-954077270_CAS-Insights-Hero-Image.jpg)
This biomaterials Insights Report explores eight key areas transforming healthcare with self-healing implants, targeted drug delivery, and more.
![IP Services](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/661d6544fedcf2eecb6ad1d8_ip_services-capabiliteis-1217903400-16-9.webp)
![IP Services](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/661d641dda6d0d4f54a4334d_Saari.David_lr_crop.webp)
David Saari, Ph.D., shares his thoughts on blending science, law, and technology in IP, highlighting the competitive edge of multidisciplinary expertise.
![Human brain](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/661996611cecc2d0d3f0e163_GettyImages-928080812-1280x1280.jpg)
![Human brain](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65664c5adf81e2c0183b3914_Rumiana-Tenchov2.webp)
While no cure exists for PolyQ diseases like Huntington's, new breakthroughs, therapies, and research could change that.
![Mauro and Chris](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/66199cbc6ab50a6bef54a694_Mauro-and-Chris-photo.jpg)
![Mauro and Chris](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/661d6efbcd5b8ff47359375b_mauro-300x300-cas-headshots.webp)
We speak with Mauro Mileni, Ph.D., and Chris Roth, Ph.D., about how their company is leveraging specific technology to fill an innovative drug pipeline.
![Multi-walled Carbon Nanotube](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/660b11d4b0bc4209c66721ac_GettyImages-181900530_CAS-Insights-Hero-Image.webp)
Carbon nanotubes (CNTs) hold immense promise for batteries, composites, sensors, and more. Discover emerging trends on overcoming challenges and cutting edge applications.
![Close up of invasive colon cancer cells](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/660b152cd509f2b7d087348a_GettyImages-142021970_CAS-Insights-Hero-Image.webp)
Biomarkers could help doctors catch cancer earlier, cure it more frequently, and perform treatments with fewer risks.
![Particles data wave](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65d8c85667f4e4af6661357f_GettyImages-1341258962_CAS-Insights-Hero-Image.webp)
![Particles data wave](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65552931e98e0f62c065620b_CASGENENGIMG100984221209-Jen-Sexton-headshot.webp)
Data-driven technologies play a pivotal role in swift analysis and quick response to chemical threats.
![A close up of computer chips](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65e74ec941619ea1747eae5b_GettyImages-1153450785.webp)
Recycling semiconductors was once a far-off dream. However, new research and technology shows that this could become reality.
![Sugar substitute on color background](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/660b18e3e247ebc5ca11c003_GettyImages-1409397697_CAS-Insights-Hero-Image.webp)
![Sugar substitute on color background](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65a010c57e8a791572ad3449_Krittika-Ralhan.webp)
Explore the science behind sweeteners, their health impact, and emerging alternatives.
![DNA sequencing illustration](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/66747995abfcc60e3b2d85f5_GettyImages-670895255_CAS-Insights-Hero-Image.jpg)
See key insights on emerging RNA IP trends and possibilities for future innovations in this executive summary.
![Different types of tablets in blister packaging and jars on the table.](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65cf8119f6ef06d6af622f5d_GettyImages-1648498226_CAS-Insights-Hero-Image.webp)
As antimicrobial resistance becomes a larger problem, new approaches to battling infections are emerging.
![A close-up image of several translucent, spherical cells with a blue outer layer and an orange-red, textured inner core. These cells appear to be floating in a blue, hazy environment, giving a microscopic view typically seen in biological studies.](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65d51e666d2d9590a9f5faf3_GettyImages-1786394525.webp)
The landscape of exosomes has become highly competitive. See all the recent investments, innovations, and commercial opportunities.
![Green Fertilizer](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65cf7a03238d4e090e321b34_INSGENENGINFO101882-Sustainable-Fertilizer-Infographic-Social-Cutdown.webp)
See how new innovations like biorefineries, waste repurposing, and materials are reshaping the future of sustainable fertilizers.
![Entrepreneur discussing with colleagues on video call](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65cf7e1dd554e0abad3cc653_GettyImages-1369567908_CAS-Insights-Hero-Image.webp)
![Entrepreneur discussing with colleagues on video call](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65664db43ac339e9410b9589_Janet-Sasso_0.webp)
Experts from Lawrence Livermore National Lab, Oak Ridge National Lab, The Ohio State University, and CAS discuss major research trends in 2024.
![Two Asian female friends visiting her female patient in the hospital ward](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65c12bd488efdfba788f46da_GettyImages-1425645808_CAS-Insights-Hero-Image.webp)
![Two Asian female friends visiting her female patient in the hospital ward](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65664c5adf81e2c0183b3914_Rumiana-Tenchov2.webp)
As cancer is projected to increase, finding stronger therapeutics is more urgent. Biomarkers offer a potential solution for better diagnosis and treatment.
![Liquid based cytology microscope slide for pap smear test](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65c278ff61dc0de6133b4c1d_GettyImages-1431379640_CAS-Insights-Hero-Image.webp)
![Liquid based cytology microscope slide for pap smear test](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65664c5adf81e2c0183b3914_Rumiana-Tenchov2.webp)
CAS and Excelra delved into data surrounding biomarkers and their relationship to cancer to identify key targets for future study.
![Smart farm and Automatic robot mechanical arm harvesting vegetables](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65b2a1b1b93277a8f5550444_GettyImages-1447095423_CAS-Insights-Hero-Image.webp)
Discover how AI in the food industry is transforming production, innovation, and sustainability. Learn how AI can help you create smarter and more efficient food solutions.
![A healthcare worker in blue protective gear, including a mask and face shield, is standing beside a seated patient in a hospital setting. The patient, with an arm cuff, is looking at a monitor displaying vital signs. Sunlight filters through large windows behind them.](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65a0155aa1881cbe9dea123e_GettyImages-1404912459_CAS-Insights-Hero-Image.webp)
Immunotherapy is advancing with new approaches like CAR-T cell therapy, antibody-drug conjugates, and even checkpoint inhibitors.
![swirly picture](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65832e03044447447de3d7a2_INSGENENGSOC101819-Drug-Discovery-Article-1920x1080-Hero.webp)
The pharma industry is tackling major drug discovery challenges in several new ways. Have they been successful?
![a mother holds her baby girl in her arms.](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/653c22e7d3ea1bc901240c23_GettyImages-1165575967_CAS-Insights-Hero-Image.webp)
![a mother holds her baby girl in her arms.](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6566315f3d290c69237830d8_author-GaryGustafson.webp)
了解靶向共价抑制剂如何通过激活RAS基因和PI3Kα等以往不可成药的靶点,彻底改变癌症治疗。 本次专家网络研讨会由Totus Medicines和CAS共同举办,展示了有关共价抑制剂的最新趋势和见解。
![Scientists in lab coats conducting experiments in a laboratory.](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/658052cf36c4eda7458cad36_INSGENENGSOC101707-Covalently-Linked-Inhibitors-Article-1920x1080-Hero.webp)
Drugs created with covalent inhibitors are becoming more popular than other types, owing to their unique mechanism of action.
![一群人登上诺贝尔奖的舞台](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65676ff7aacabaa283626629_nanaka-adachi-nobelprize.webp)
正值诺贝尔颁奖季,让我们一同探索那些尚未获得诺贝尔奖且最容易被忽视的各类见解。 从 OLED 到 MOF 再到 mRNA 疗法等多个领域,这些见解重塑了科学和技术。 加入 LinkedIn 上的对话。
![Arrow pointing from xray of a human gut to a person's brain](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65679504fabacd5d57a5e7ef_The-Gut-Microbiome-Brain-Alliance.webp)
![Arrow pointing from xray of a human gut to a person's brain](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65664db43ac339e9410b9589_Janet-Sasso_0.webp)
在本次网络研讨会上,CAS、拜耳和加州理工学院的专家将探讨肠道微生物群与大脑之间的奇妙联系。 了解脑肠轴如何影响从肠易激综合症 (IBS) 到自闭症患者的健康情况,以及操纵微生物组如何提供新的治疗策略。
![黑色背景上的蓝白线条](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/656797dcae5e48970f12a308_GettyImages-1419830522_CAS-Insights-Hero-Image.webp)
了解 CAS、拉霍亚免疫学研究所 (LaJolla Institute for Immunology) 和 Avidity Biosciences 的专家如何探索生物学和化学在癌症、疫苗等新兴疗法中的融合。 此处查看回顾概要和幻灯片。
![GettyImages-1414912077_CAS-Insights-Hero-Image](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/658b37c98e690fcd9267171d_GettyImages-1414912077_CAS-Insights-Hero-Image.webp)
这份单页执行摘要围绕抗衰老策略和相关疗法,重点介绍了干细胞疗法、处方药和生活方式改变等方面的新兴趋势、新方法和未来机遇。 其中包括临床试验管线分析的关键收获和新兴治疗策略的前景展望。
![Technicians are assembling batteries for use in electric vehicles](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/657388b4dd6ab1bc4a75052c_GettyImages-1313787631_CAS-Insights-Hero-Image.webp)
Graphene-based supercapacitor technologies are being levied for real-world applications as a battery alternative.
![casgenenginfo101246-3D 打印信息图表英雄-1920x1080](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6580618cac75b8721c277eac_CASGENENGINFO101246-3D-Printing-Infographic-Hero-1920x1080%20(1).webp)
在我们的新信息图中了解 3D 打印如何最终改变生物医学应用。看看材料和方法的进步如何重塑了以下领域:组织、移植和器官的采购、新的药物递送方法以及手术环境和伤口护理的进步。
![A 3D printed heart laying on a table](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65679c949b8f839bf30615ff_biomedical-3d-printing.webp)
![A 3D printed heart laying on a table](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65679b41593bda5d14226093_Chia-Wei%20Hsu.webp)
了解外泌体(即自然界的脂质纳米颗粒)如何重塑药物递送以及从癌症到心血管疾病等疾病的治疗。 查看我们最近开展的 ACS 网络研讨会,向梅奥诊所 (Mayo Clinic)、Direct Biologics 和 Aruna Bio 的专家学习。 立即观看录播视频,并阅读完整洞察报告。
![女性实验室技术员](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/658068df818cdb7383d31dbd_1920x1080-infographic-hero.webp)
在我们的新信息图中了解RNA疗法如何改变医学。了解这项尖端技术在癌症、传染病、肝脏和代谢性疾病中的应用、挑战和机遇。了解这个快速发展的领域中有关关键纳米颗粒、新兴类型RNA和修改序列的最新趋势和数据。
![PEGylated-LPNs-Blog-HERO-1920x1080](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/657372a5d77d6068b34e96fb_PEGylated-LPNs-Blog-HERO-1920x1080.webp)
![PEGylated-LPNs-Blog-HERO-1920x1080](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65664c5adf81e2c0183b3914_Rumiana-Tenchov2.webp)
了解如何克服 PEG 免疫原性对聚乙二醇化脂质纳米颗粒药物递送安全性和有效性的影响这一挑战。 本文综述了目前解决 PEG 免疫原性的最新研究进展,从阐明抗 PEG 抗体生成的影响因素到开发新型药物载体或优化给药和剂量。
![pegylated-journal-Hero-1920x1080](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65847fbd0744fe41ceb0d6dd_PEGylated-Journal-Hero-1920x1080.jpg)
这篇经过同行评审的期刊发表在《生物偶联化学》杂志上,展示了如何使用聚乙二醇化脂质纳米颗粒来输送mRNA疫苗和其他药物、疫苗的免疫原性问题以及提高疗效和安全性的新设计新方法。
![PRD1 噬菌体结构的分子模型](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/657b5bc4e32367c3eea1514e_Lipid-Nanoparticles-1920x1080.webp)
学习如何解决聚乙二醇免疫原性,这是一项影响药物递送聚乙二醇化脂质纳米颗粒的安全性和有效性的挑战。了解这一尖端领域的最新研发趋势、市场数据和机会,包括 COVID-19 疫苗和各种利用这些纳米颗粒的当前和未来药物。
![本·R·塔夫脱](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/659c739d95c85ee9c3382687_ben-r-taft-1920x1080.webp)
![本·R·塔夫脱](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/661d6de66275c91d4713fbda_ben-taft-300x300-cas-headshots.webp)
在本期 CAS 系列文章《药物开发的挑战与机遇》中,我们与 Via Nova Therapeutics 的化学高级总监 Ben Taft 讨论了构效关系研究和生物活性数据的潜在前沿。
![GettyImages-1415655606_CAS-Insights-Hero-Image](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/657a2d4638a7eed3e4e7d6b6_GettyImages-1415655606_CAS-Insights-Hero-Image.webp)
![GettyImages-1415655606_CAS-Insights-Hero-Image](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65664c5adf81e2c0183b3914_Rumiana-Tenchov2.webp)
肠道微生物组是一个由数万亿细菌组成的复杂生态系统,这些细菌存活在我们的消化道中,具有提供免疫力、改善心理健康和提供治疗选择等健康益处。 近年来,人们对微生物组疗法治疗各种疾病的潜力越来越感兴趣。 随着我们对肠道微生物组的理解不断加深,我们有望在未来几年看到微生物组疗法的更多进展。
![细菌是微生物组的一部分](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65805597e4242aaae1cffdaa_gettyimages-1359393303.webp)
本报告对肠道微生物组进行了全面的景观分析,包括其组成、功能以及在健康和疾病中的作用。本文是与拜耳公司合作撰写的,讨论了有关基于微生物组的疗法、微生物群、益生菌及其可能影响的各种健康状况的最新研究,例如肥胖、糖尿病、炎症性肠病甚至心理健康障碍。
![Illustration of the gut microbiome](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/659eb05a10fa54f601a1954e_gettyimages-1124678428_1.webp)
这份发表在《ACS 化学神经科学》杂志上的同行评审出版物详细介绍了有关肠道微生物组领域最新发展趋势的局势分析。 它深入探讨了微生物组疗法、最新方法、新科学、临床渠道和该领域的关键参与者。
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微塑料是一个全球性问题,可以被动物和人类摄入。它们还可以在土壤和水中聚集,而破坏坏生态系统。越南来越多的证书表明,微塑料可能对健康有害。本执行摘要重点介绍微塑料的关键来源、健康风险及可以采取的 directures micures
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同行评审期刊文章是与中国国家自然科学基金会、中国科学院国家科学图书馆以及美国化学学会下属的中科院合作发表在《有机化学与有机快报》杂志上,内容涉及全球合成有机化学研究的现状,重点是酶催化、光催化和绿色化学。