CAS Chemical Safety Library™ Advisory Panel
The CAS Chemical Safety Library is overseen by an advisory panel of experts from CAS and others in the commercial, academic, and non-profit sectors.
CAS 和皮斯托亚联盟的合作伙伴关系
CAS 和皮斯托亚联盟致力于通过促进公开分享的关键安全数据，保障全球科研界的安全。
皮斯托亚联盟是一个全球非营利成员组织，其使命是推动协作，促进各组织的合作共赢。 努力保障化学工业和学术界的实验室和人身安全是实现该使命的关键。
CAS 是美国化学会旗下的专业科学信息解决方案提供机构，致力于安全保障是该组织的核心价值观，并提供独特的信息管理专业知识和技术：
- 收录和管理高质量的科学内容，包括 CAS REGISTRY®（物质数据库）
- 先进的科学信息研究平台，如 CAS SciFinder Discovery Platform 和 STN IP Protection Suite
- 定制科学信息服务
About the CAS Chemical Safety Library
The CAS Chemical Safety Library is a repository for the scientific community to capture and confidentially share hazardous reaction information from real-world laboratory experiences to improve safety and reduce incidents across the chemical enterprise. A brief history of the repository:
- Fall 2016
A presentation by Mark Manfredi (Bristol Myers Squibb) at ACS Fall 2016, “Ensuring That Lessons Learned Are Not Forgotten, Leveraging ELN to Transform the Safety Paradigm”, inspired the idea for a simple crowd-sourced hazardous reaction data collection system. Further championed by Ramesh Durvasula (Lilly), the Pistoia Alliance led the development of the Chemical Safety Library.
- Spring 2017
Hazardous reaction information from Bristol Myers Squibb was added to the Pistoia Alliance Chemical Safety Library, which was then expanded through datathons, hackathons, and data extraction from C&EN Safety Letters and other sources.
- Winter 2018 - Spring 2020
A simplified submission system helped the Pistoia Alliance Chemical Safety Library reach 138 records. Data was made available to users through .csv file requests and the entire library was shared with PubChem (National Library of Medicine).
- Summer 2020 - Spring 2024
CAS began hosting the Pistoia Alliance Chemical Safety Library and established the Advisory Panel, chaired by Carmen Nitsche (The Cambridge Crystallographic Data Centre) and Mark Manfredi (Bristol Myers Squibb) to drive future development. A strategic partnership with the Campus Safety, Health, and Environmental Management Association (CSHEMA) was also established and extended outreach to academia. A reusable data collection protocol (Chemical Safety Library in a Box) was developed through data mining projects with Purdue University and the University of Minnesota.
- Spring 2024
Chemical Safety Library in a Box was deployed at UCLA and promoted at CSHEMA Safety Week. In March, a datathon was hosted at ACS Spring 2024 to expand the information collection. The resource was officially renamed “CAS Chemical Safety Library” after ownership was transferred from the Pistoia Alliance to CAS. Today, the CAS Chemical Safety Library includes more than 500 records.