CAS InsightsTM
Accelerating your scientific progress by revealing unique connections and perspective at the intersection of science, technology, and innovation.
![A visual representation of a virus.](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/659eaa48dbcbcf86d1a1fb39_MonkeyPox-thumbnailhero.webp)
![A visual representation of a virus.](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65664db43ac339e9410b9589_Janet-Sasso_0.webp)
With recent headlines on monkeypox, learn more about the research landscape, scientific profiles, and currently available therapies. A deeper understanding of the published science enables clarity and insight on this emerging news story.
![Nanoparticles in drug delivery, conceptual illustration](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/66d0e3d935f8122db13547aa_GettyImages-1423889653_CAS-Insights-Hero-Image.jpg)
![Nanoparticles in drug delivery, conceptual illustration](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65664c5adf81e2c0183b3914_Rumiana-Tenchov2.webp)
Nanoscale drug delivery systems can improve treatment for cancer, autoimmune diseases, HIV, and other conditions
![Cropped shot of two female scientists working with a computer and a digital microscope in a laboratory](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/66c4d3f1fde749c9c558931c_GettyImages-1187071494_CAS-Insights-Hero-Image-flipped.jpg)
![Cropped shot of two female scientists working with a computer and a digital microscope in a laboratory](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/659d92c42ced2335b2f8256f_julian-ivanov.webp)
How QSAR modeling and machine learning identify potential new drug compounds for kinase inhibitors
![Inflamed knee healing, illustration](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/66bfc7b8eb97a3bdcd3845cc_GettyImages-1607119465_CAS-Insights-Hero-Image.jpeg)
![Inflamed knee healing, illustration](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65664db43ac339e9410b9589_Janet-Sasso_0.webp)
Biomaterials are making an impact on health and medicine. Experts from CAS, Ortholevo, and Westlake University discuss the full landscape.
![Network and data wave](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/66b2634d88b61ff0f5dc8ac7_GettyImages-2078445001_CAS-Insights-Hero-Image.jpg)
Nanofibers, nanoplastics, and more are gaining research interest. See more nanotechnology breakthroughs through the lens of a CAS TrendScape analysis.
![Degradation of motor neurons, illustration](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/66aa5582c78e9ebf9168b6e5_GettyImages-1328336839-2048x2048.jpg)
Rare diseases are difficult to treat, diagnose, and identify. As such, researchers are spending more effort in better understanding and treating these illnesses.
![Neurons and Microglia](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/66aa584a156b861ac9002f16_GettyImages-1623197497_CAS-Insights-Hero-Image.jpg)
![Neurons and Microglia](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65664c5adf81e2c0183b3914_Rumiana-Tenchov2.webp)
How combination therapies including drug repurposing, cell therapy, and genetic therapy are leading to improved treatment of rare diseases.
![Close-up of finger with small nano device](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/66a11da6e86a514a03032f33_INSGENENGSOC102127-Nanotechnology-mind-map-2-Hero.webp)
Combining advanced technologies with human curation identifies emerging trends in nanotechnology research.
![Three women jumping over hurdles on a track during a race.](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/669aa06dcbb06306057ad685_INSGENENGSOC102131-Olympic-Sport-Technology-Article-1920x1080-Hero.webp)
![Three women jumping over hurdles on a track during a race.](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/669a6c89990312d00ab779af_preeti-jain.webp)
How do science and sportswear fit together? Explore the innovations in fabrics and materials that are creating sportswear that help athletes boost their performance.
![A macro shot of a vibrant blue liquid with numerous bubbles.](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6697cf45429fa6d1fe77bb08_cas-challenges-oppurtunities-1920x1080.webp)
![A macro shot of a vibrant blue liquid with numerous bubbles.](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6697ca87b3fef701d07fd5d4_zoheb-hassan-phd.webp)
Dr. Zoheb Hassan, a senior consultant at Frost & Sullivan, shares his insights on the data management complexities that define the current drug discovery landscape.
![Parkinsons disease nerve cells, illustration](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/667f10c3f1162630760ac36f_GettyImages-932736856_CAS-Insights-Hero-Image.webp)
![Parkinsons disease nerve cells, illustration](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65664c5adf81e2c0183b3914_Rumiana-Tenchov2.webp)
Parkinson's disease can be distressing for families, so scientists are working hard to find potential treatments by repurposing drugs and more.
![Two Radiologists Looking At MRI Scan On Computer](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/668ed10827199a8526c23c23_GettyImages-1312649676_CAS-Insights-Hero-Image.jpg)
![Two Radiologists Looking At MRI Scan On Computer](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65664c5adf81e2c0183b3914_Rumiana-Tenchov2.webp)
Uncover the latest advancements in understanding and treating neurodegenerative diseases like Alzheimer’s, Parkinson’s, and Huntington’s.
![Mosaic of Shattered Plastic](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6687fa65e410f9ca035ab914_GettyImages-1174748370_CAS-Insights-Hero-Image.jpg)
Recycling plastics can be challenging with traditional methods, leading to developments in chemical plastic recycling technology.
![Scientist using computer in laboratory](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/665630178896a5c734fae00f_GettyImages-1194829395_CAS-Insights-Hero-Image.jpeg)
![Scientist using computer in laboratory](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6656269366142d5c7a6816c2_CAS_HDSHOT_Prince_M_20240524113149_5x4.jpg)
Revealing the search engine functionality that balances breadth and precision for effective scientific research.
![Multi-walled Carbon Nanotube](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/667453f114451ce2a6ea2d3f_GettyImages-181900530_CAS-Insights-Hero-Image.jpg)
Biomedicine, batteries, and more could be revolutionized by carbon nanotubes. See the full range of their applications.
![Brain activity human brain damage neural network](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6655fc2f707825861f42f3d4_GettyImages-1410795105_CAS-Insights-Hero-Image.jpg)
This detailed technical report, published in collaboration with Westlake University, discusses the biomaterials landscape and how this field is rapidly changing.
![middle aged woman with mobility issues](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6655f4d45b39fb2df7add062_GettyImages-1172515013_CAS-Insights-Hero-Image.jpg)
![middle aged woman with mobility issues](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65664c5adf81e2c0183b3914_Rumiana-Tenchov2.webp)
Sharing new research on inverse vaccines, potential new breakthroughs in treating autoimmune diseases like multiple sclerosis, type 1 diabetes and celiac disease
![Chain of amino acid or bio molecules called protein](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6655f9d7074789ae00e32c92_GettyImages-1337292061_CAS-Insights-Hero-Image.jpg)
![Chain of amino acid or bio molecules called protein](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65737bed58a2d9cdd363650a_magesh%20passport%20size%20photo.webp)
See how self-healing materials that include reversible chemical bonds are reshaping wound care, drug delivery & tissue regeneration in our latest landscape analysis.
![Male Doctor and Patient Examining brain MRI](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6655f72f393c15ac97050e32_GettyImages-1412852343_CAS-Insights-Hero-Image.webp)
![Male Doctor and Patient Examining brain MRI](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65664c5adf81e2c0183b3914_Rumiana-Tenchov2.webp)
Biomarkers, personalized medicine and gene therapies are fueling research breakthroughs. Discover new treatments targeting genetics and protein buildup to manage this devastating disease.
![Organic, bio cosmetics healthy concept with Petri Dishes](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6650c9a5a28beeec4baafb63_GettyImages-1357162123_CAS-Insights-Hero-Image.jpg)
Learn about the shift towards sustainable and natural ingredients in cosmetics, supported by data from the CAS Content Collection™.
![Human brain](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65738d1500058c938ae33bcb_GettyImages-1410795090_CAS-Insights-Hero-Image.webp)
Bioelectronics: Merging man and machine. Explore the latest advancements in brain-computer interfaces, materials, and their potential to revolutionize medicine.
![baby feet](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6650cdfaa290bc2f4cefcae0_GettyImages-1530326519_CAS-Insights-Hero-Image.webp)
![baby feet](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6650cee28206339303109d50_jean-marc-150x150-headshots%20(1).webp)
Nanoscale materials are bridging the gap between nanotechnology and bioelectronics, paving the way for highly sensitive biosensors.
![Molecular model of messenger ribonucleic acid mRNA](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/66421322277b4accaff6f2ee_GettyImages-1450368712_CAS-Insights-Hero-Image.webp)
Different types of antisense oligonucleotide therapies, such as exosomes and nanoparticles, offering new hope in genetic medicine.
![Human cell and virus cells](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6642166d4ee026b29025ce35_GettyImages-182506763_CAS-Insights-Hero-Image.jpg)
![Human cell and virus cells](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65552931e98e0f62c065620b_CASGENENGIMG100984221209-Jen-Sexton-headshot.webp)
Learn how emerging trends in AI are impacting CBRNE threat detection and mitigation.
![A digital art image depicting a dark, circular center surrounded by a radiant halo of glowing blue and green light strands, resembling an eye or an abstract explosion. The background is a deep blue, enhancing the vibrancy of the colors.](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6642179c8cd214f452d9591f_GettyImages-1495604593_CAS-Insights-Hero-Image.jpg)
Unlock the potential of nanotechnology. Explore breakthroughs and challenges in energy, biomedicine, and more in our executive summary.
![Abstract digital artwork featuring vibrant, multicolored peaks and valleys. The image showcases a dynamic blend of pink, purple, blue, and black hues, creating a visually striking and futuristic landscape with a sense of depth and movement.](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/662a57de9be24d9652ba4b3b_GettyImages-954077270_CAS-Insights-Hero-Image.jpg)
This biomaterials Insights Report explores eight key areas transforming healthcare with self-healing implants, targeted drug delivery, and more.
![IP Services](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/661d6544fedcf2eecb6ad1d8_ip_services-capabiliteis-1217903400-16-9.webp)
![IP Services](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/661d641dda6d0d4f54a4334d_Saari.David_lr_crop.webp)
David Saari, Ph.D., shares his thoughts on blending science, law, and technology in IP, highlighting the competitive edge of multidisciplinary expertise.
![Salt and pepper shakers on a restaurant table, with sweeteners nearby.](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/661eb4fe5e2d426ec4788079_GettyImages-1000353706_CAS-Insights-Hero-Image-resized.jpg)
Uncover the science behind sweeteners, their health impacts, R&D trends, and investment data.
![Human brain](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/661996611cecc2d0d3f0e163_GettyImages-928080812-1280x1280.jpg)
![Human brain](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65664c5adf81e2c0183b3914_Rumiana-Tenchov2.webp)
While no cure exists for PolyQ diseases like Huntington's, new breakthroughs, therapies, and research could change that.
![Mauro and Chris](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/66199cbc6ab50a6bef54a694_Mauro-and-Chris-photo.jpg)
![Mauro and Chris](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/661d6efbcd5b8ff47359375b_mauro-300x300-cas-headshots.webp)
We speak with Mauro Mileni, Ph.D., and Chris Roth, Ph.D., about how their company is leveraging specific technology to fill an innovative drug pipeline.
![Multi-walled Carbon Nanotube](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/660b11d4b0bc4209c66721ac_GettyImages-181900530_CAS-Insights-Hero-Image.webp)
Carbon nanotubes (CNTs) hold immense promise for batteries, composites, sensors, and more. Discover emerging trends on overcoming challenges and cutting edge applications.
![Close up of invasive colon cancer cells](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/660b152cd509f2b7d087348a_GettyImages-142021970_CAS-Insights-Hero-Image.webp)
Biomarkers could help doctors catch cancer earlier, cure it more frequently, and perform treatments with fewer risks.
![Particles data wave](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65d8c85667f4e4af6661357f_GettyImages-1341258962_CAS-Insights-Hero-Image.webp)
![Particles data wave](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65552931e98e0f62c065620b_CASGENENGIMG100984221209-Jen-Sexton-headshot.webp)
Data-driven technologies play a pivotal role in swift analysis and quick response to chemical threats.
![nuclear battery](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/660b15008daa7fa27beba6f6_INSGENENGSOC101903-Nuclear-Battery-Article-1920x1080-Hero%20(1).webp)
Pocket-sized nuclear batteries are here. Discover their potential and limitations, from powering wearables to tackling radioactive waste.
![A close up of computer chips](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65e74ec941619ea1747eae5b_GettyImages-1153450785.webp)
Recycling semiconductors was once a far-off dream. However, new research and technology shows that this could become reality.
![Sugar substitute on color background](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/660b18e3e247ebc5ca11c003_GettyImages-1409397697_CAS-Insights-Hero-Image.webp)
![Sugar substitute on color background](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65a010c57e8a791572ad3449_Krittika-Ralhan.webp)
Explore the science behind sweeteners, their health impact, and emerging alternatives.
![white blood cells](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/660b1a05e9c564289508fa58_white_blood_cells_attacking_1920x1080.webp)
![white blood cells](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6580b7e97f3afe5d908f98de_Kavita-Iyer-300x300.webp)
Experts discuss emerging trends in immuno-oncology, data challenges, and opportunities ahead for cancer researchers.
![DNA sequencing illustration](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/66747995abfcc60e3b2d85f5_GettyImages-670895255_CAS-Insights-Hero-Image.jpg)
See key insights on emerging RNA IP trends and possibilities for future innovations in this executive summary.
![Different types of tablets in blister packaging and jars on the table.](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65cf8119f6ef06d6af622f5d_GettyImages-1648498226_CAS-Insights-Hero-Image.webp)
As antimicrobial resistance becomes a larger problem, new approaches to battling infections are emerging.
![A close-up image of several translucent, spherical cells with a blue outer layer and an orange-red, textured inner core. These cells appear to be floating in a blue, hazy environment, giving a microscopic view typically seen in biological studies.](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65d51e666d2d9590a9f5faf3_GettyImages-1786394525.webp)
The landscape of exosomes has become highly competitive. See all the recent investments, innovations, and commercial opportunities.
![Green Fertilizer](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65cf7a03238d4e090e321b34_INSGENENGINFO101882-Sustainable-Fertilizer-Infographic-Social-Cutdown.webp)
See how new innovations like biorefineries, waste repurposing, and materials are reshaping the future of sustainable fertilizers.
![Entrepreneur discussing with colleagues on video call](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65cf7e1dd554e0abad3cc653_GettyImages-1369567908_CAS-Insights-Hero-Image.webp)
![Entrepreneur discussing with colleagues on video call](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65664db43ac339e9410b9589_Janet-Sasso_0.webp)
Experts from Lawrence Livermore National Lab, Oak Ridge National Lab, The Ohio State University, and CAS discuss major research trends in 2024.
![Two Asian female friends visiting her female patient in the hospital ward](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65c12bd488efdfba788f46da_GettyImages-1425645808_CAS-Insights-Hero-Image.webp)
![Two Asian female friends visiting her female patient in the hospital ward](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65664c5adf81e2c0183b3914_Rumiana-Tenchov2.webp)
As cancer is projected to increase, finding stronger therapeutics is more urgent. Biomarkers offer a potential solution for better diagnosis and treatment.
![Liquid based cytology microscope slide for pap smear test](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65c278ff61dc0de6133b4c1d_GettyImages-1431379640_CAS-Insights-Hero-Image.webp)
![Liquid based cytology microscope slide for pap smear test](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65664c5adf81e2c0183b3914_Rumiana-Tenchov2.webp)
CAS and Excelra delved into data surrounding biomarkers and their relationship to cancer to identify key targets for future study.
![Smart farm and Automatic robot mechanical arm harvesting vegetables](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65b2a1b1b93277a8f5550444_GettyImages-1447095423_CAS-Insights-Hero-Image.webp)
Discover how AI in the food industry is transforming production, innovation, and sustainability. Learn how AI can help you create smarter and more efficient food solutions.
![A healthcare worker in blue protective gear, including a mask and face shield, is standing beside a seated patient in a hospital setting. The patient, with an arm cuff, is looking at a monitor displaying vital signs. Sunlight filters through large windows behind them.](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65a0155aa1881cbe9dea123e_GettyImages-1404912459_CAS-Insights-Hero-Image.webp)
Immunotherapy is advancing with new approaches like CAR-T cell therapy, antibody-drug conjugates, and even checkpoint inhibitors.
![genetic engineering and dna microarray](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65a94cce3088880fe4bf0917_GettyImages-1154532721_CAS-Insights-Hero-Image.webp)
![genetic engineering and dna microarray](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65a010c57e8a791572ad3449_Krittika-Ralhan.webp)
AI is redefining natural product drug discovery by unlocking diverse candidates from plants, microbes, and more.
![Antimicrobial susceptibility test Antibiogram Antibiotic resistance bacteria](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65a0113448a534029c5737f3_GettyImages-1360169225_CAS-Insights-Hero-Image.webp)
![Antimicrobial susceptibility test Antibiogram Antibiotic resistance bacteria](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65a010c57e8a791572ad3449_Krittika-Ralhan.webp)
Antimicrobial-resistant infections are a global public health crisis. New solutions like AI, alternative therapeutics, and innovations in materials offer a way to fight back.
![Path to San Juan de Gaztelugatxe, Basque Country, Spain](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/658d9ea527da22dba19f11ec_GettyImages-1035400870_CAS-Insights-Hero-Image.webp)
Stay ahead of the latest scientific breakthroughs that are accelerating the landscape of innovation and will transform global science in 2024
![Ground Plastic Flakes](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65835acc7203e7c0186392b8_gettyimages-1331268240.jpg)
![Ground Plastic Flakes](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65552931e98e0f62c065620b_CASGENENGIMG100984221209-Jen-Sexton-headshot.webp)
Learn how digital transformation is reducing waste and creating new revenue streams for companies as they repurpose waste byproducts.
![Microscopic view of human blood cells stained for analysis. The image shows a mix of light brown, small elongated cells (likely red blood cells) and larger, round dark purple cells (likely white blood cells or cells stained for identification).](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6580b835ce3a957ecf054c03_INSGENENGSOC101791-Emerging-trends-Immuno-oncology-research-article-1920x1080-Hero.webp)
![Microscopic view of human blood cells stained for analysis. The image shows a mix of light brown, small elongated cells (likely red blood cells) and larger, round dark purple cells (likely white blood cells or cells stained for identification).](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6580b7e97f3afe5d908f98de_Kavita-Iyer-300x300.webp)
Immuno-oncology has the potential to treat cancer without sacrificing the patient's wellbeing.
![swirly picture](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65832e03044447447de3d7a2_INSGENENGSOC101819-Drug-Discovery-Article-1920x1080-Hero.webp)
The pharma industry is tackling major drug discovery challenges in several new ways. Have they been successful?
![CAS data experts Mark Schmidt, Jeff Wilson, and Nicole Stobart](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65738aabba36bc4fb9264cf1_CAS_INSIGHTS_20231201143622_5DA_0776.webp)
![CAS data experts Mark Schmidt, Jeff Wilson, and Nicole Stobart](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/661d701dcab7b284a393c313_mark-300x300-cas-headshots.webp)
In this article, we speak with Nicole Stobart, Jeff Wilson, and Mark Schmidt, about how CAS is using authority constructs to index biological molecules.
![GettyImages-1142858578_CAS-Insights-Hero-Image](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/657b4bdf4cb03ec1d128e408_GettyImages-1142858578_CAS-Insights-Hero-Image.webp)
![GettyImages-1142858578_CAS-Insights-Hero-Image](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65552931e98e0f62c065620b_CASGENENGIMG100984221209-Jen-Sexton-headshot.webp)
Pharmaceutical manufacturers are investigating ways to cultivate insights from dark formulations data, turning once-hidden knowledge into drug discoveries.
![water droplets on a green surface](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65676dbc2ba20519d311b5db_GettyImages-1317109051_CAS-Insights-Hero-Image.webp)
With the push towards increased sustainability, here are four ways coatings manufacturers are making use of renewable feedstock for their own products.
![blue light in the dark](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/655529e6f259d46c13707778_Formulations-Drug-Repurposing-hero.webp)
![blue light in the dark](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65552931e98e0f62c065620b_CASGENENGIMG100984221209-Jen-Sexton-headshot.webp)
As the drug repurposing market grows, pharmaceutical manufacturers are investigating ways to cultivate insights from dark formulations data, turning once hidden insights into drug repurposing innovations.
![A person sitting at a table prepping medicine](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/655b64b0fe6a771162b586f9_INSGENENGSOC101294-Weight-loss-drug-1920x1080-Hero.webp)
![A person sitting at a table prepping medicine](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/655b6471773495214e22089c_terra-williams-300x300.webp)
Ozempic, Wegovy, and Mounjaro are part of a new class of semaglutides (GLP-1 receptor agonists) that help treat obesity and diabetes by regulating blood sugar and appetite.
![sunlight shining through the water](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/655b67bed137a62611e751de_GettyImages-1485125421_CAS-Insights-Hero-Image.webp)
![sunlight shining through the water](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65737bed58a2d9cdd363650a_magesh%20passport%20size%20photo.webp)
Learn how photocatalysis can produce clean hydrogen from water and solar energy and why it is crucial for decarbonization.
![a mother holds her baby girl in her arms.](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/653c22e7d3ea1bc901240c23_GettyImages-1165575967_CAS-Insights-Hero-Image.webp)
![a mother holds her baby girl in her arms.](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6566315f3d290c69237830d8_author-GaryGustafson.webp)
CAS and Totus Medicines discuss how targeted covalent inhibitors are revolutionizing cancer treatments.
![a close up of a hexagonal structure.](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/653c2350f23803a35a584399_CASGENENGSOC101682-Nanotube-Article-HERO-1920x1080.webp)
Single-walled carbon nanotubes have great potential in several industries from renewable energy to drug delivery.
![Profile shot of Iddo Friedberg](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/653c223bf5621ffd39d66fb7_Iddo-friedberg-1920x1080.webp)
![Profile shot of Iddo Friedberg](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/653c223bf5621ffd39d66fb7_Iddo-friedberg-1920x1080.webp)
Iddo Friedberg, an expert in protein function prediction, shares how current prediction models are performing and what current bottlenecks remain.
![a child holding a stuffed animal](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65661bac771cd2447dbd3f6a_INSGENENGWHP101675-Covalently-Linked-Inhibitors-Executive-Summary-Social-Article-1920x1080-Hero.webp)
Covalent inhibitors were once avoided due to negative side effects, but new drugs have changed the landscape.
![Scientists in lab coats conducting experiments in a laboratory.](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/658052cf36c4eda7458cad36_INSGENENGSOC101707-Covalently-Linked-Inhibitors-Article-1920x1080-Hero.webp)
Drugs created with covalent inhibitors are becoming more popular than other types, owing to their unique mechanism of action.
![a close-up of a virus](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6566434e0da4f4f1674604ff_INSGENENGWHP101674-Antibody-Drug-Conjugates-Executive-Summary-1920x1080-Hero.webp)
More than 100 antibody-drug conjugates are in clinical trials. These therapeutics combine the targeting abilities of antibodies with the power of chemotherapy to change cancer treatment.
![a close-up of a molecule](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65664c9136f7ce3f0f7d9c2f_casgenengsoc101701-antibody-drug-conjugates-article-1920x1080-hero.webp)
![a close-up of a molecule](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65664c5adf81e2c0183b3914_Rumiana-Tenchov2.webp)
Since 2018, research interest in antibody-drug conjugates has increased exponentially, due to their potential in the fight against cancer.
![a group of people on a stage at nobel](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65676ff7aacabaa283626629_nanaka-adachi-nobelprize.webp)
CAS scientists discuss overlooked ideas that have yet to win a Nobel Prize. From OLEDs and MOFs to mRNA therapeutics and more, these ideas have reshaped science and technology.
![abstract animation of a network of connected lines and dots connected by a network of connected lines.](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6567862e43bdf606746f499f_GettyImages-1165763968_CAS-Insights-Hero-Image.webp)
Incomplete prior art searches and analyses can lead to costly mistakes, leaving innovations and the value of intellectual property open to huge risk.
![A series of connected blue dots](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/655535b46415c2baf6b441b5_gettyimages-1212079174_cas-insights-hero-image.webp)
![A series of connected blue dots](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65552931e98e0f62c065620b_CASGENENGIMG100984221209-Jen-Sexton-headshot.webp)
Digital initiatives are transforming the chemical industry, allowing for faster innovation and a sustainable future.
![a man and woman pointing at a computer screen](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65678b957006aa636bbf7037_GettyImages-1093747624_CAS-Insights-Hero-Image.webp)
Patentability assessments in scientific industries come with significant challenges due to their complexity. However, CAS has tools designed to address these issues.
![Arrow pointing from xray of a human gut to a person's brain](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65679504fabacd5d57a5e7ef_The-Gut-Microbiome-Brain-Alliance.webp)
![Arrow pointing from xray of a human gut to a person's brain](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65664db43ac339e9410b9589_Janet-Sasso_0.webp)
CAS, Bayer, and Caltech explore how the gut-brain axis influences health from IBS to autism.
![A digital illustration featuring concentric circles with glowing blue lines and colorful particles radiating from the center, creating a dynamic, futuristic tunnel effect. The background is dark, enhancing the vibrant colors and intricate patterns.](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65553617f5a3a297974b40a9_GettyImages-1340683419_CAS-Insights-Hero-Image.webp)
![A digital illustration featuring concentric circles with glowing blue lines and colorful particles radiating from the center, creating a dynamic, futuristic tunnel effect. The background is dark, enhancing the vibrant colors and intricate patterns.](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65552931e98e0f62c065620b_CASGENENGIMG100984221209-Jen-Sexton-headshot.webp)
Strategies to unlock dark data in the pharmaceutical industry. Reveal data insights and accelerate innovation through digitization and knowledge management.
![blue and white lines on a black background](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/656797dcae5e48970f12a308_GettyImages-1419830522_CAS-Insights-Hero-Image.webp)
CAS, the LaJolla Institute for Immunology, and Avidity Biosciences explore the convergence of biology and chemistry in emerging therapeutics for cancer, vaccines, and more.
![blue swirl with green light](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65679a8dd9aa12b296be8920_GettyImages-1151435289_CAS-Insights-Hero-Image.webp)
![blue swirl with green light](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65552931e98e0f62c065620b_CASGENENGIMG100984221209-Jen-Sexton-headshot.webp)
Digital initiatives are transforming the pharmaceutical industry, allowing for faster drug development and expanded treatment options.
![Birds-eye view of two cargo ships](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65679b8a624f3bfe4b1e1036_GettyImages-1414740197_CAS-Insights-Hero-Image.webp)
![Birds-eye view of two cargo ships](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65679b41593bda5d14226093_Chia-Wei%20Hsu.webp)
Catalysts and catalysis have transformed our world, from ancient times to modern sustainability. Learn about the latest research trends and innovations.
![A plant-based burger on a table](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65679e9d4b51dac132aa1cb8_GettyImages-1325924756_CAS-Insights-Hero-Image.webp)
With consumers changing their diets for personal and health reasons, innovation to increase quality and variety creates a diverse and competitive market.
![A collection of colorful liquids in glass containers.](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/659593fbb1c325c2f352c94b_GettyImages-1388434533_CAS-Insights-Hero-Image.webp)
Hero ingredients can help create more advanced and versatile formulations than ever before as consumers slim down their cosmetic routines.
![Successful rocket take off into the starry sky with the milky way](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/659e9e6ed409141c74a884c1_GettyImages-1440522663_CAS-Insights-Hero-Image.webp)
Chemistry is powering space exploration with rocket fuel and engine technologies. Discover the advantages and challenges of using LOX/LH2 as a propellant for the Artemis mission.
![INSGENENGBRO101249-CAS-Insights-Executive-Summary-Sustainable-Catalysts-1920x1080-Hero](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/658b3667cac73994ba43b0f2_INSGENENGBRO101249-CAS-Insights-Executive-Summary-Sustainable-Catalysts-1920x1080-Hero.webp)
Catalysts have been enabling green chemistry with applications in many industries.
![Senior chemistry professor writing on the board](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/659dba0fdda3a78118e5b349_gettyimages-957979682_cas-insights-hero-image.webp)
![Senior chemistry professor writing on the board](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/659dba3044b385afe107fecc_philippe-ayala-mugshot.webp)
ChatGPT has redefined the conversation around AI but is it right for scientific research? Find out more about the path ahead for LLMs in science.
![INSGENENGSOC101307-mRNA-Social-Graphics-1920x1080-Hero](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/659c4214dcf898fd1299a0e5_INSGENENGSOC101307-mRNA-Social-Graphics-1920x1080-Hero.webp)
Thanks to mRNA vaccines, which have revolutionized the fight against COVID-19, we can treat cancer by harnessing the power of the immune system.
![GettyImages-1491277474_CAS-Insights-Hero-Image](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6580543c54c1fcce95bab814_GettyImages-1491277474_CAS-Insights-Hero-Image.webp)
Biomaterials like hydrogels, lipid nanoparticles, and exosomes are reshaping the landscape of drug delivery, diagnosis, and therapeutics.
![SERVICES_CAROUSEL_workflow_1920X1080_72d_wpatc](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/659ebc92b150eed14e54b1c7_SERVICES_CAROUSEL_workflow_1920X1080_72d_wpatch.webp)
Learn how leveraging patent tools and strategies can accelerate your path toward comprehensive searches and stronger insights.
![CASGENENGSOC101277-Anti-Aging-Article-HERO-1920x1080](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/657a2ace0fb460b10e107965_CASGENENGSOC101277-Anti-Aging-Article-HERO-1920x1080.webp)
![CASGENENGSOC101277-Anti-Aging-Article-HERO-1920x1080](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65664c5adf81e2c0183b3914_Rumiana-Tenchov2.webp)
Discover the latest in anti-aging treatment strategies to promote health and longevity, including stem cell therapies, hyaluronic acid, senolytics, gene therapy, and more.
![GettyImages-1414912077_CAS-Insights-Hero-Image](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/658b37c98e690fcd9267171d_GettyImages-1414912077_CAS-Insights-Hero-Image.webp)
Research in anti-aging treatments has reached a pivotal point. How do new treatments, drugs, and clinical trials compare to time-tested practices?
![IP Insights Competitive Edge Blog hero](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/659ebe9798dd06f44e07d8d4_IP-insights-blog-hero.webp)
Accelerate and improve the ROI of your IP and R&D initiatives by partnering with an industry and IP expert.
![INSGENENGSOC101264-Microplastics-Infographics-1920x1080-Thumbnail](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65805c2c06048030f14d73c9_INSGENENGSOC101264-Microplastics-Infographics-1920x1080-Thumbnail.webp)
Microplastics have infiltrated our entire world, even down to the water we drink and food we eat. Researchers are looking at new ways to address them.
![Jefferson Parker](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/659c72e8cfa70d9762251d98_jefferson_parker.webp)
![Jefferson Parker](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/661d6e72fb308323e37ee9fb_jefferson-300x300-cas-headshots.webp)
We talk with Jefferson Parker of NullSet Informatics Solutions, about sequence analysis for drug discovery and the frontiers for AI in computational biology.
![Technicians are assembling batteries for use in electric vehicles](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/657388b4dd6ab1bc4a75052c_GettyImages-1313787631_CAS-Insights-Hero-Image.webp)
Graphene-based supercapacitor technologies are being levied for real-world applications as a battery alternative.
![Molecular glues blog thumbnail](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/659db11f936891a70f245a0d_molecular-glues-blog-thumbnail.webp)
Induced-proximity target protein degradation (TPD) is a ground-breaking strategy in drug discovery that has emerged recently.
![SIPPSGENENGSOC101244230621-Foundations-IP-Articles-Hero-1920x1080](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/659ebb9e5998d7aaeeafaa5b_SIPPSGENENGSOC101244230621-Foundations-IP-Articles-Hero-1920x1080.webp)
A successful patent landscape analysis can maximize opportunities and de-risk your company's R&D program and other initiatives.
![INSGENENGWHP101107-insights-Summary-Hero-1920x1080](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/658b38e1e659285289880cf6_INSGENENGWHP101107-insights-Summary-Hero-1920x1080%20(2).webp)
mRNA vaccines created for COVID-19 have led to a slew of new research in mRNA therapeutics.
![GettyImages-507492447_CAS-Insights-Hero-Image](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/659c6100a7b20a6091fe750e_GettyImages-507492447_CAS-Insights-Hero-Image.webp)
What is dark data, and how can it be used to unlock data insights and accelerate innovation for R&D?
![CASGENENGINFO101246-3D-Printing-Infographic-Hero-1920x1080](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/6580618cac75b8721c277eac_CASGENENGINFO101246-3D-Printing-Infographic-Hero-1920x1080%20(1).webp)
Discover how advances in 3D printing materials and approaches have reshaped tissues and organ sourcing, drug delivery methods, and wound care.
![A 3D printed heart laying on a table](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65679c949b8f839bf30615ff_biomedical-3d-printing.webp)
![A 3D printed heart laying on a table](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65679b41593bda5d14226093_Chia-Wei%20Hsu.webp)
Experts from Mayo Clinic, Direct Biologics, and Aruna Bio discuss how 3D bioprinting is reshaping disease treatment.
![Female-lab-technician](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/658068df818cdb7383d31dbd_1920x1080-infographic-hero.webp)
Investment in RNA has grown beyond vaccines. Cancer, infectious diseases, and even liver diseases have all been identified for RNA medicines.
![Close-Up Of Green Capsules In Blister Packs](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/659ecfa28e6a5b4dc744c388_gettyimages-1199914429_cas-insights-hero-image.webp)
Learn five ways to reduce waste and use biodegradable materials to develop sustainable sterile packaging options for medical devices.
![PEGylated-LPNs-Blog-HERO-1920x1080](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/657372a5d77d6068b34e96fb_PEGylated-LPNs-Blog-HERO-1920x1080.webp)
![PEGylated-LPNs-Blog-HERO-1920x1080](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65664c5adf81e2c0183b3914_Rumiana-Tenchov2.webp)
PEG immunogenicity affects the safety and efficacy of PEGylated lipid nanoparticles for drug delivery. Much work is being done to circumvent this challenge in applying these polymers.
![PEGylated-Journal-Hero-1920x1080](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/65847fbd0744fe41ceb0d6dd_PEGylated-Journal-Hero-1920x1080.jpg)
Learn how PEGylated lipid nanoparticles are used to deliver mRNA vaccines and other drugs, the immunogenicity concerns with vaccines, and emerging approaches on new designs to increase efficacy and safety.
![Close-up view of a blue and purple virus particle with a hexagonal patterned surface and protruding protein spikes under a microscope. The background shows another blurred virus particle, giving a sense of depth and magnification.](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/657b5bc4e32367c3eea1514e_Lipid-Nanoparticles-1920x1080.webp)
PEG immunogenicity is a challenge that affects the safety and efficacy of PEGylated lipid nanoparticles for drug delivery.
![Ben R. Taft](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/659c739d95c85ee9c3382687_ben-r-taft-1920x1080.webp)
![Ben R. Taft](https://cdn.prod.website-files.com/650867962272bf8f15c1034b/661d6de66275c91d4713fbda_ben-taft-300x300-cas-headshots.webp)
We chat with Ben Taft, Sr. Director of Chemistry at Via Nova Therapeutics, about SAR studies and the possible frontiers for bioactivity data.