CAS Insights^TM

Experts from CAS, Harvard Medical School, Procter & Gamble, and Cedars-Sinai Medical Center discuss health aging research.

PROTACs are driving small molecule drug development to treat cancer, neurodegenerative diseases and more

Discover how artificial intelligence in pharma can enhance drug repurposing by leveraging dark data, ensuring data diversity, and improving data quality.

The opportunities and challenges facing the development of goldene

Discover how CAS leverages advanced data management and predictive models to revolutionize drug discovery in this conversation with industry leaders.

While CAR-T cell therapy is mostly used for cancers, it has shown promising results in treating autoimmune diseases, HIV, and more

As solar panel usage increases, researchers are looking for new methods to tackle PV waste.

The GIP and GLP-1 function shows promising results in treating cardiovascular and neurodegenerative conditions.

Three categories of breakthroughs that have been awarded the Nobel Prize in Chemistry in the last forty years

Why are there no FDA approved TBK1 (TANK-binding kinase) inhibitors on the market, despite the key role it plays in the pathophysiology of many diseases.

Science and wearable tech go hand in hand to provide athletes with precise, personalized information to improve their performance.

With recent headlines on monkeypox, learn more about the research landscape, scientific profiles, and currently available therapies. A deeper understanding of the published science enables clarity and insight on this emerging news story.

Nanoscale drug delivery systems can improve treatment for cancer, autoimmune diseases, HIV, and other conditions

How QSAR modeling and machine learning identify potential new drug compounds for kinase inhibitors

Biomaterials are making an impact on health and medicine. Experts from CAS, Ortholevo, and Westlake University discuss the full landscape.

Nanofibers, nanoplastics, and more are gaining research interest. See more nanotechnology breakthroughs through the lens of a CAS TrendScape analysis.

Rare diseases are difficult to treat, diagnose, and identify. As such, researchers are spending more effort in better understanding and treating these illnesses.

How combination therapies including drug repurposing, cell therapy, and genetic therapy are leading to improved treatment of rare diseases.

Combining advanced technologies with human curation identifies emerging trends in nanotechnology research.

How do science and sportswear fit together? Explore the innovations in fabrics and materials that are creating sportswear that help athletes boost their performance.

Dr. Zoheb Hassan, a senior consultant at Frost & Sullivan, shares his insights on the data management complexities that define the current drug discovery landscape.

Parkinson's disease can be distressing for families, so scientists are working hard to find potential treatments by repurposing drugs and more.

Uncover the latest advancements in understanding and treating neurodegenerative diseases like Alzheimer’s, Parkinson’s, and Huntington’s.

Recycling plastics can be challenging with traditional methods, leading to developments in chemical plastic recycling technology.

Revealing the search engine functionality that balances breadth and precision for effective scientific research.

Biomedicine, batteries, and more could be revolutionized by carbon nanotubes. See the full range of their applications.

This detailed technical report, published in collaboration with Westlake University, discusses the biomaterials landscape and how this field is rapidly changing.

Sharing new research on inverse vaccines, potential new breakthroughs in treating autoimmune diseases like multiple sclerosis, type 1 diabetes and celiac disease

See how self-healing materials that include reversible chemical bonds are reshaping wound care, drug delivery & tissue regeneration in our latest landscape analysis.

Biomarkers, personalized medicine and gene therapies are fueling research breakthroughs. Discover new treatments targeting genetics and protein buildup to manage this devastating disease.

Learn about the shift towards sustainable and natural ingredients in cosmetics, supported by data from the CAS Content Collection™.

Bioelectronics: Merging man and machine. Explore the latest advancements in brain-computer interfaces, materials, and their potential to revolutionize medicine.

Nanoscale materials are bridging the gap between nanotechnology and bioelectronics, paving the way for highly sensitive biosensors.

Different types of antisense oligonucleotide therapies, such as exosomes and nanoparticles, offering new hope in genetic medicine.

Learn how emerging trends in AI are impacting CBRNE threat detection and mitigation.

Unlock the potential of nanotechnology. Explore breakthroughs and challenges in energy, biomedicine, and more in our executive summary.

This biomaterials Insights Report explores eight key areas transforming healthcare with self-healing implants, targeted drug delivery, and more.

David Saari, Ph.D., shares his thoughts on blending science, law, and technology in IP, highlighting the competitive edge of multidisciplinary expertise.

Uncover the science behind sweeteners, their health impacts, R&D trends, and investment data.

While no cure exists for PolyQ diseases like Huntington's, new breakthroughs, therapies, and research could change that.

We speak with Mauro Mileni, Ph.D., and Chris Roth, Ph.D., about how their company is leveraging specific technology to fill an innovative drug pipeline.

Carbon nanotubes (CNTs) hold immense promise for batteries, composites, sensors, and more. Discover emerging trends on overcoming challenges and cutting edge applications.

Biomarkers could help doctors catch cancer earlier, cure it more frequently, and perform treatments with fewer risks.

Data-driven technologies play a pivotal role in swift analysis and quick response to chemical threats.

Pocket-sized nuclear batteries are here. Discover their potential and limitations, from powering wearables to tackling radioactive waste.

Recycling semiconductors was once a far-off dream. However, new research and technology shows that this could become reality.

Explore the science behind sweeteners, their health impact, and emerging alternatives.

Experts discuss emerging trends in immuno-oncology, data challenges, and opportunities ahead for cancer researchers.

See key insights on emerging RNA IP trends and possibilities for future innovations in this executive summary.

As antimicrobial resistance becomes a larger problem, new approaches to battling infections are emerging.

See how new innovations like biorefineries, waste repurposing, and materials are reshaping the future of sustainable fertilizers.

Experts from Lawrence Livermore National Lab, Oak Ridge National Lab, The Ohio State University, and CAS discuss major research trends in 2024.

As cancer is projected to increase, finding stronger therapeutics is more urgent. Biomarkers offer a potential solution for better diagnosis and treatment.

CAS and Excelra delved into data surrounding biomarkers and their relationship to cancer to identify key targets for future study.

Discover how AI in the food industry is transforming production, innovation, and sustainability. Learn how AI can help you create smarter and more efficient food solutions.

Immunotherapy is advancing with new approaches like CAR-T cell therapy, antibody-drug conjugates, and even checkpoint inhibitors.

AI is redefining natural product drug discovery by unlocking diverse candidates from plants, microbes, and more.

Antimicrobial-resistant infections are a global public health crisis. New solutions like AI, alternative therapeutics, and innovations in materials offer a way to fight back.

Stay ahead of the latest scientific breakthroughs that are accelerating the landscape of innovation and will transform global science in 2024

Learn how digital transformation is reducing waste and creating new revenue streams for companies as they repurpose waste byproducts.

Immuno-oncology has the potential to treat cancer without sacrificing the patient's wellbeing.

The pharma industry is tackling major drug discovery challenges in several new ways. Have they been successful?

In this article, we speak with Nicole Stobart, Jeff Wilson, and Mark Schmidt, about how CAS is using authority constructs to index biological molecules.

Pharmaceutical manufacturers are investigating ways to cultivate insights from dark formulations data, turning once-hidden knowledge into drug discoveries.

With the push towards increased sustainability, here are four ways coatings manufacturers are making use of renewable feedstock for their own products.

As the drug repurposing market grows, pharmaceutical manufacturers are investigating ways to cultivate insights from dark formulations data, turning once hidden insights into drug repurposing innovations.

Ozempic, Wegovy, and Mounjaro are part of a new class of semaglutides (GLP-1 receptor agonists) that help treat obesity and diabetes by regulating blood sugar and appetite.

Learn how photocatalysis can produce clean hydrogen from water and solar energy and why it is crucial for decarbonization.

CAS and Totus Medicines discuss how targeted covalent inhibitors are revolutionizing cancer treatments.

Single-walled carbon nanotubes have great potential in several industries from renewable energy to drug delivery.

Iddo Friedberg, an expert in protein function prediction, shares how current prediction models are performing and what current bottlenecks remain.

Covalent inhibitors were once avoided due to negative side effects, but new drugs have changed the landscape.

Drugs created with covalent inhibitors are becoming more popular than other types, owing to their unique mechanism of action.

More than 100 antibody-drug conjugates are in clinical trials. These therapeutics combine the targeting abilities of antibodies with the power of chemotherapy to change cancer treatment.

Since 2018, research interest in antibody-drug conjugates has increased exponentially, due to their potential in the fight against cancer.

Today, OLEDs are appearing everywhere on phones, media players, portable gaming systems, lighting, and even car radios.

It is surprising that the chemical synthesis of DNA has not won a Nobel prize because it transformed DNA synthesis from a specialized exploration into a widely used research, diagnostic, and forensic tool.

Traditionally, many key benefits of a drug or pharmaceutical cannot be realized because of their poor solubility, high toxicity, or stability problems. However, the use of dendrimers as drug delivery vehicles can solve many of these problems.

Today, OLEDs are appearing everywhere on phones, media players, portable gaming systems, lighting, and even car radios.

While much of the world has already seen the impact that mRNA has had on vaccines for COVID-19, it may be time to recognize Dr. Katalin Karikó and Dr. Drew Weissman for their outstanding contributions to nucleoside modifications to suppress RNA immunogenicity on top of their pioneering work.

Gut microbiome research has expanded exponentially in recent years, with fecal microbiota transplantation (FMT) at the forefront of this research.

CAS scientists discuss overlooked ideas that have yet to win a Nobel Prize. From OLEDs and MOFs to mRNA therapeutics and more, these ideas have reshaped science and technology.

Incomplete prior art searches and analyses can lead to costly mistakes, leaving innovations and the value of intellectual property open to huge risk.

Digital initiatives are transforming the chemical industry, allowing for faster innovation and a sustainable future.

Patentability assessments in scientific industries come with significant challenges due to their complexity. However, CAS has tools designed to address these issues.

CAS, Bayer, and Caltech explore how the gut-brain axis influences health from IBS to autism.

Strategies to unlock dark data in the pharmaceutical industry. Reveal data insights and accelerate innovation through digitization and knowledge management.

CAS, the LaJolla Institute for Immunology, and Avidity Biosciences explore the convergence of biology and chemistry in emerging therapeutics for cancer, vaccines, and more.

Digital initiatives are transforming the pharmaceutical industry, allowing for faster drug development and expanded treatment options.

Catalysts and catalysis have transformed our world, from ancient times to modern sustainability. Learn about the latest research trends and innovations.

With consumers changing their diets for personal and health reasons, innovation to increase quality and variety creates a diverse and competitive market.

Hero ingredients can help create more advanced and versatile formulations than ever before as consumers slim down their cosmetic routines.

Chemistry is powering space exploration with rocket fuel and engine technologies. Discover the advantages and challenges of using LOX/LH2 as a propellant for the Artemis mission.

Catalysts have been enabling green chemistry with applications in many industries.

ChatGPT has redefined the conversation around AI but is it right for scientific research? Find out more about the path ahead for LLMs in science.

Thanks to mRNA vaccines, which have revolutionized the fight against COVID-19, we can treat cancer by harnessing the power of the immune system.

Biomaterials like hydrogels, lipid nanoparticles, and exosomes are reshaping the landscape of drug delivery, diagnosis, and therapeutics.

Learn how leveraging patent tools and strategies can accelerate your path toward comprehensive searches and stronger insights.

Discover the latest in anti-aging treatment strategies to promote health and longevity, including stem cell therapies, hyaluronic acid, senolytics, gene therapy, and more.

Research in anti-aging treatments has reached a pivotal point. How do new treatments, drugs, and clinical trials compare to time-tested practices?